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Use of better starting doses in individuals who will be not opioid tolerant might bring about lethal respiratory melancholy with 1st dose; selection of First dose should really take note of diploma of opioid tolerance, patient's standard situation, clinical position, concurrent medications, style and severity of suffering, and chance components for

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Jeuk komt in de palliatieve fase regelmatig voor bij patiënten met cholestase of als paraneoplastisch verschijnsel. Deze laatste (neurogene) jeuk wijst op een disbalans van neurotransmittoren in de achterhoorn en kan op dat niveau medicamenteus worden aangepakt.Dat morfine geen geschikt middel is om te sederen is ook sommige artsen en verpleegkund

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